Despite overcoming a 28-10 deficit with 3:30 left in the third quarter, Purdue was unable to beat visiting Indiana (8-4), falling 44-41 in double overtime. Trailing 28-17 entering the fourth quarter, Purdue (4-8) managed to come back and to tie the score at 31 apiece with 2:48 left in the game.

After both teams traded touchdowns in the first overtime with Purdue converting a fourth and goal from the 6-yard line, Purdue was held to a field goal in the second overtime, allowing a 1-yard rush by Indiana to end the game.

Purdue's offense exploded the game, totaling 589 yards as sophomore quarterback Aidan O'Connell went 28 of 49 with 408 yards, three touchdowns and one interception. Sophomore running back Zander Horvath led the Boilermaker rushing attack, gaining 164 yards on 23 carries and two touchdowns. On defense, the Purdue defensive line gave Indiana quarterback trouble as it recorded five sacks and three pass breakups.